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MicroPulse P3® Device
For Non-Incisional Glaucoma Treatment With MicroPulse® Transscleral Laser Therapy
- A success rate of 60% to 80%1-17
- Achieves IOP reduction of 30% to 45%1, 3, 6, 9-15, 17, 18
- Durability of up to 72 months with 3 retreatments19
- Over 120,000 patients treated in 60 countries
- Leaves future treatment options open
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Schedule a hands-on demo Schedule a no-obligation demo to see for yourself how MicroPulse Technology and IRIDEX’s Family of Products can take YOUR practice to the next level.
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Re-Thinking Glaucoma Care
MICROPULSE® TRANSSCLERAL LASER THERAPY (TLT) A compelling combination of safety, effectiveness, durability and repeatability all in a nonincisional approach to Glaucoma Care. MicroPulse Transscleral Laser Therapy via the MicroPulse P3 Device offers you and your patients a treatment paradigm which can be introduced prior to, in conjunction with and following all other available glaucoma treatment options, and the ability to treat at several different time points throughout the course of the disease. - A success rate of 60% to 80%1-17
- Leaves future treatment options open
- Achieves IOP reduction of 30% to 45%1, 3, 6, 9-15, 17, 18
- For moderate, severe, and refractory glaucoma
- Durability of up to 72 months with 3 retreatments19
- Used in 38 of the 39 best hospitals in the United States*
- Reduction in drug burden in eye drops and oral medications1-4, 6-13, 18
- Revised probe now available with improved ease of use, visualization, fit, and coupling
- Low cost per mmHg reduction versus other interventions
- Limited amount of immediate follow-up
- Patient downtime is significantly low
- Low investment for high utility
- Economic savings to patients
- Covered under CPT 66710 ($400 -$1,934)
1 Zaarour K, et al. J Glaucoma 2019. 2 Subramaniam K, et al. Cornea 2019. 3 Nguyen AT, et al. Eur J Ophthalmol 2019. 4 Barac R, et a. Romanian J Ophthalmol 2018. 5 Sanchez FG, et al. Arch Soc Esp Oftalmol 2018. 6 Lee JH, et al. J Glaucoma 2017. 7 Sarrafpour S, et al. Ophthalmology Glaucoma 2019. 8 Awoyesuku EA, et al. JAMMR 2019. 9 Abdelrahman AM, et al. J Glaucoma 2018. 10 Aquino MC, et al. Clin Exp Ophthalmol 2015. 11 Jammal AA, et al. Arq Bras Oftalmol 2019. 12 Tan A, et al. Clin Experiment Ophthalmol 2010. 13 Williams AL, et al. J Glaucoma 2018. 14 Varikuti VNV, et al. J Glaucoma 2019. 15 Souissi S, et al. Eur J Ophthalmol 2019. 16 Magacho L, et al. Lasers Med Sci 2019. 17 Magacho L, et al. J Glaucoma 2019. 18 Yelenskiy A, et al. J Glaucoma 2018. 19 Aquino M, et al. European Glaucoma Society 2016. * As ranked by U.S. News and World Report.
SURGICAL GUIDE
- A viscous, liquid interface (e.g. methyl cellulose) must be utilized to ensure proper laser energy distribution. Place a drop on the undersurface of the probe footplate. Reapply as necessary. Not using a liquid interface could result in loss of up to 50% of energy.
- Orient the probe with the wide, curved side (bunny ears) aligned at the surgical limbus. Be sure to view from directly above to avoid placement error because of parallax.
- Maintain the footplate of the probe flat against the conjunctiva throughout the treatment with constant, gentle pressure. Do not rock the probe while sweeping.
- Use 2000 mW to 2500 mW @ 50 seconds x 31.3% duty cycle.
- Sweep the probe along the limbus in an arc of 150 degrees for 10 seconds (avoid the 3 and 9 o’clock positions). Maintain a constant velocity during each pass.
- Reverse the direction and repeat for a total of 5 passes.
WEBINARS
Webinar on Monday, April 13, 2020: The revised MicroPulse P3® Device: What You Need to Know Register Now Webinar with Dr. Jason Bacharach: How I Am Treating Glaucoma During the COVID-19 Pandemic Webinar with Dr. Brian Francis: Utilizing MicroPulse® Transscleral Laser Therapy in and outside my glaucoma practice Webinar with Dr. Nathan Radcliffe: Optimizing MicroPulse® TSCPC for Multiple Glaucoma Types Webinar with Dr. Brian Jerkins: The Role of MicroPulse® TSCPC for Glaucoma
STUDIES
 | Venkata Varikuti: Outcomes of MicroPulse Transscleral Cyclophotocoagulation in Eyes With Good Central Vision
Journal of Glaucoma
2019
Download Now | | Zaid Khoueir: Outcomes of Micropulse Transscleral Cyclophotocoagulation in Uncontrolled Glaucoma Patients
Glaucoma Journal
March 2019
Download Now | | Vital Costa: Prospective evaluation of mTSCPC in refractory glaucoma 1 yr results
Arquivos Brasileiros de Oftalmologia
2019
Download Now | | Aleksandr Yelenskiy: Patient Outcomes Following MicroPulse Transscleral Cyclophotocoagulation: Intermediate-term Results
Glaucoma Journal
October 2018
Download Now | | Ahmed M. Abdelrahman: Micropulse Versus Continuous Wave Transscleral Cyclophotocoagulation in Glaucoma Journal
October 2018
Download Now | | Alice Williams: Clinical Efficacy and Safety Profile of Micropulse Transscleral Cyclophotocoagulation in Refractory Glaucoma
Glaucoma Journal
May 2018
Download Now | | Ramona Barac: Choroidal thickness increase after micropulse transscleral cyclophotocoagulation
Romanian Joournal of Opthalmology
April 2018
Download Now | | Jun Hui Lee: Outcome of Micropulse Laser Transscleral Cyclophotocoagulation on Pediatric Versus Adult Glaucoma Patients
Glaucoma Journal
October 2017
Download Now | | Matthew Emanuel: Micropulse Cyclophotocoagulation: Initial Results in Refractory Glaucoma
Glaucoma Journal
August 2017
Download Now | | Edward Bendel: mTSCPC Observational Report
2017
Download Now | | Maria Cecilia Aquino: Long-term Efficacy of Micropulse Diode Transscleral Cyclophotocoagulation in the Treatment of Refractory Glaucoma
National University Health System
2017
Download Now | | Rolando Toyos: Clinical Outcomes of Micropulsed Transcleral Cyclophotocoagulation in Moderate to Severe Glaucoma
Journal of Clinical & Experimental
Opthalmology 2016
Download Now | | Sarah Kuchar: Treatment outcomes of micropulse transscleral cyclophotocoagulation in advanced glaucoma
Springer-Veriag London
December 2015
Download Now | | Maria Cecilia Aquino: Micropulse versus continuous wave transscleral diode cyclophotocoagulation in refractory glaucoma: a randomized exploratory study
Clinical & Experimental
Opthalmology 2014
Download Now | | Anna Tan: Micropulse transscleral diode laser cyclophotocoagulation in the treatment of refractory glaucoma
Clinical & Experimental
Opthalmology 2010
Download Now | | Antonio Maria Fea: MicroPulse diode laser trabeculoplasty (MDLT): A phase II clinical study with 12 months follow-up
Clinical Ophthalmology
2008
Download Now | | MicroPulse P3: Peer Reviewed Studies Summary
Download Now |
ARTICLES
Outcome of MicroPulse Transscleral Photocoagulation in different Types of Glaucoma
December 2019 - Clinical Ophthalmology
By Ahmed Al Habash, MD Micropulse Transscleral Diode Laser Photocoagulation: What We Do and Don't Know
December 2019 - Medscape
By Shuchi B. Patel, MD MicroPulse Trans-scleral Laser Therapy for Glaucoma
December 2019 - Glaucoma Physician
By Vital Costa, MD Outcomes of MicroPulse Transscleral Cyclophotocoagulation in Eyes With Good Central Vision
October 2019 - Journal of Glaucoma
By Venkata Varikuti, MD MicroPulse cyclophotocoagulation effective in keratoplasty eyes
August 2019 – EyeWorld
By Robert Noecker, MD Cook County Health presents glaucoma studies at ARVO
May 2019 – Ocular Surgery News
By Michael C. Giovingo, MD Study shows MicroPulse laser controls IOP after keratoplasty
May 2019 – Ocular Surgery News
By Jessica Minjy Kang, MD Avoiding issues from inflow procedures
May 2019 – Ophthalmology Times
By Jeffrey Kammer, MD Subthreshold laser shows favorable foveal remodeling after macular hole closure
May 2019 – Ocular Surgery News
By Boris Stanzel, MD Standardizing techniques for MicroPulse cyclophotocoagulation needed
April 2019 - Healio Ocular Surgery News
By Jella An, MD Outcomes of Micropulse Transscleral Cyclophotocoagulation in Uncontrolled Glaucoma Patients
March 2019 – Glaucoma Journal
By Ziad Khoueir, MD Transscleral MicroPulse CPC in Open-Angle Glaucoma
February 2019 – Glaucoma Today
By Fahad Khan, MD; and Rohit Krishna, MD The role of MicroPulse therapy
February 2019 – Ophthalmology Management
By Ahad Mahootchi, MD Which MIGS for which patient?
January 2019 – Ophthalmology Times
By Brian A. Francis, MD, MS
2018
Micropulse Transscleral Cyclophotocoagulation: A Hypothesis for the Ideal Parameters
November 2018 - Medical Hypothesis, Discovery &Innovation Ophthalmology Journal
By Tomas M. Grippo, MD Try this laser before you go to the OR
October 2018 - Ocular Surgery News
By Melissa Toyos, MD Video: MicroPulse for mild to moderate stage glaucoma
August 2018 - Ocular Surgery News
By Sandra Fernando-Sieminski, MD MicroPulse not just for end-stage glaucoma patients
August 2018 - Ocular Surgery News
By Sandra Fernando-Sieminski, MD Reassessing TSCPC’s role
August 2018 - The Ophthalmologist
By David Gossage, DO Micropulse P3™ (MP3) Laser for Glaucoma: An Innovative Therapy
August 2018 – JOCGP
By Maria Cecilia Aquino, MD Efficacy and safety of Micropulse® transscleral cyclophotocoagulation in glaucoma
August 2018 – Archivos Espanola
By F.G. Sancheza, MD MicroPulse stimulates cells
May 2018 - Ocular Surgery News
By Melissa Toyos, MD Micropulse cyclophotocoagulation minimizes post-treatment sequelae
May 2018 - Ocular Surgery News
By Soshian Sarrafpour, MD MicroPulse cyclophotocoagulation — the ultimate in flexibility
March 2018 - Ocular Surgery News
By Melissa Toyos, MD MicroPulse technology reduces IOP in wide range of glaucomatous eyes
February 16, 2018 - Ocular Surgery News
By Shan Lin, MD
2017 Glaucoma Articles & Videos
Applying micropulse transscleral cyclophotocoagulation for early-stage glaucoma
November 2017 - Ophthalmology Times
By Robert J. Noecker, MD MicroPulse technology allows safe treatment of glaucoma
November 2017 - Ocular Surgery News
By David Gossage, DO Video: Micropulse cyclophotocoagulation a safe alternative to incisional glaucoma procedures
October 2017 - Ocular Surgery News
By Marc Toeteberg-Harms, MD New Laser Therapies for Glaucoma
September 2017 - Cataract & Refractive Surgery Today
By Nisha Chadha, MD
VIDEOS
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Iridex Launches Revised Micropulse P3 Device For Glaucoma
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Advantages of MicroPulse P3 Cyclophotocoagulation
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Treating Glaucoma with the Cyclo G6 Laser - Long-Term Results
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Webinar with Dr. Nathan Radcliffe: Optimizing MicroPulse TSCPC for Multiple Glaucoma Types
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Webinar with Dr. Brian Jerkins: The Role of MicroPulse TSCPC for Glaucoma
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Dr. Takashi Fujishiro, MD talks about MicroPulse® TSCPC by Cyclo G6
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Dr. Nathan Radcliffe Discusses Experience with Cyclo G6 Laser
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Testimonial Dr Vital Paulino Costa Spanish
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Treating Glaucoma With MicroPulse Laser Therapy
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MicroPulse P3 Procedure for Glaucoma: Beyond Late Stage
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MicroPulse CPC Glaucoma Treatment and Patient’s Profiles
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Updates from the MicroPulse Aqueous Dynamics Study in Early or Moderate POAG
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IRIDEX MicroPulse ESCRS 2018 Symposium Q&A
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IRIDEX at the American Academy of Ophthalmology 2018
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Cyclo G6 Glaucoma Laser System for Non-Incisional Treatment
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Treating Glaucoma with the Cyclo G6 Laser - Long-Term Results
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Láser Cyclo G6 Para Glaucoma en Hechos de TV Azteca
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Glaucoma Laser Treatment Now Available in Russia - Cyclo G6 Glaucoma Laser
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Cyclo G6™ Glaucoma Laser, an Alternative to Stents for Glaucoma - Dr. Rolando Toyos
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Laser-Assisted, Non-incisional Glaucoma Therapy
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Glaucoma Treatment With MicroPulse Therapy
The award-winning series, Innovations with Ed Begley Jr., featured IRIDEX MicroPulse therapy for glaucoma on CNBC. In this episode, three top glaucoma specialists share what it is and how it works, and three glaucoma patients share how MicroPulse therapy has helped them to control glaucoma.
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Effect of Transscleral Diode Cyclophotocoagulation AGS
The effect of Transscleral Diode Cyclophotocoagulation using MicroPulse versus Continuous Wave on Ciliary Body observed in Miyaki Apple View. John A. Moran Eye Center University of Utah. Do you ever wonder what CPC looks like inside the eye?
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IRIDEX AAO Dr Sieminski
Dr. Sandra Sieminski talks about MicroPulse ® Technology for Glaucoma. Listen along as Dr. Sieminski shares results from a 6 month study on patients treated with the Cyclo G6 ™ Glaucoma Laser System.
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EGS Symposium: MicroPulse Therapy for Glaucoma Treatment
Dr. Ziad Khoueir (Lebanon), Dr. Ronald de Crom (The Netherlands), Dr. Marc Toeteberg (Switzerland), and Dr. Karin Roswitha Pillunat (Germany) share how they are successfully treating multiple cases of glaucoma with the Cyclo G6 Glaucoma Laser and MicroPulse Technology at the European Glaucoma Society (EGS) congress in Florence, Italy.
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Cyclo G6™ Laser and MicroPulse P3 Probe Overview
Dr. Cris Cruz Colon, glaucoma specialist at the Center of Excellence in Eye Care in Miami provides an overview of the MicroPulse P3™ Probe and the IRIDEX Cyclo G6™ Glaucoma Laser System.
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Latest Data on MicroPulse Cyclophotocoagulation
In this interview from AGS 2017, Dr. Jonathan Myers discusses MicroPulse. At the meeting, the 10 posters on the MicroPulse showed good pressure reduction and success rates ranging from 50% to 80%.
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Cyclophotocoagulation with the CYCLO G6 laser
EyeWorld Interviews Dr. Shan Lin at AAO about his experience treating glaucoma with the CYCLO G6 Glaucoma Laser.
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CYCLO G6 laser for Glaucoma
Dr. Nathan Radcliffe talks with EyeWorld at AAO about how MicroPulse works and how and why he treats glaucoma with the CYCLO G6 Glaucoma Laser.
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Symposium: IRIDEX MicroPulse® Technology Revolutionizes Cyclophotocoagulation
In this symposium from ESCRS 2017, MicroPulse experts (Drs. Ziad Khoueir, Robert Noecker, and Marc Töteberg-Harms) discuss their experience using IRIDEX lasers and MicroPulse Technology to treat glaucoma.
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CYCLO G6 laser featured in the news
WTCO Local News from Savannah, GA talked to Dr. Harris about treating glaucoma with MicroPulse Laser Trabeculoplasty and MicroPulse Cyclophotocoagulation.
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MicroPulse probe transforms transscleral cyclophotocoagulation
Dr. Randy Craven tells Ophthalmology Times that MicroPulse via the CYCLO G6 Laser is demonstrating promising efficacy with better safety and tolerability than traditional TSCPC.
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Personalized Glaucoma Laser Therapy with the Titratable MicroPulse P3
Nathan Radcliffe, MD, discusses the advantages of using the MicroPulse P3 (MP3) Glaucoma Device, plus the additional benefits of providing customized cyclophotocoagulation therapy for glaucoma patients.
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Transcleral MicroPulse Laser Dynamically Alters Ciliary Muscle and Aqueous Outflow Pathways 2017
This video by Dr. Murray Johnstone provides visually controlled, real time observation of the effects of a transcleral MicroPulse 810 nm laser. The laser pulses induce shortening of the longitudinal portion of the ciliary muscle.
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Evolution in glaucoma surgery mounting with MIGS procedures
An expanding armamentarium of minimally invasive and micro-invasive glaucoma surgery (MIGS) procedures, like laser treatment with the CYCLO G6 Glaucoma Laser, are transforming glaucoma management, said Steven D. Vold, MD.
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Tratamiento para glaucoma con el laser IRIDEX Cyclo G6
El Dr. Marco Antonio Beltrán, especialista en glaucoma del Centro Oftalmológico de Sonora, en Hermosillo, Mexico, habla sobre el tratamiento para el glaucoma con el láser IRIDEX Cyclo G6 con MicroPulso - una alternativa para medicamentos y cirugías.
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MicroPulse, a New Procedure Arises to Help Fight Glaucoma
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Dr. Shan Lin explains how he treats glaucoma with MicroPulse therapy
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ABSTRACTS
| Selective Laser Trabeculoplasty vs Micropulse Laser Trabeculoplasty in Open-Angle Glaucoma
Download Now | | Histologic Changes Following Continuous Wave And Micropulse Transscleral Cyclophotocoagulation: A Randomized Comparative Study
AGS 2019
Download Now | | Transcleral Micropulse Laser (TML) Effects On Outflow System, Sclera, Ciliary Muscle (CB) & Suprachoroidal Space (SCS): Insights From High-Resolution OCT (HROCT), Real-Time Video (RTV) & Histology
AGS 2019
Download Now | | Dan Yoon: Two Meta-analyses on the Outcomes of Sequential Glaucoma Drainage Implantation vs. Cyclophotocoagulation
AGS 2019
Download Now | | Nadiya Kots-Gotlib: Outcomes of Ahmed Valve Implantation Supplemented with Limited Diode Cyclophotocoagulation
AGS 2019
Download Now | | Beatriz Aguando: TRANSSCLERAL CYCLOPHOTOCOAGULATION WITH DIODE LASER FORREFRACTORY GLAUCOMA. OUR EXPERIENCE
EGS 2018
Download Now | | Behzad Amoozgar: Comparison of Long-term Clinical Outcomes between Micropulse Transscleral Cyclophotocoagulation and Endoscopic Cyclophotocoagulation-Plus
AGS 2018
Download Now | | Brett Breshears: Two-Year Retroactive Study of G6 Transscleral Cyclophotocoagulation as a Secondary Poag Treatment
ASCRS 2018
Download Now | | Briana Gapsis: Analysis of the Relative Efficacy of Micropulse Laser Trabeculoplasty and Selective Laser Trabeculoplasty
ARVO 2018
Download Now | | Carisa Bohnak: Micropulse Transscleral Cyclophotocoagulation in the Treatment of Patients with Primarily Severe Stage Glaucoma
ASCRS April 2018
Download Now | | Catherina Goenadi: EARLY OUTCOMES OF MICROPULSE DIODE TRANSSCLERAL CYCLOPHOTOTHERAPY FOR TREATMENT OF MILD TO MODERATE GLAUCOMA
EGS May 2018
Download Now | | Catherine Sun: Comparison of Outcomes of Micropulse Laser Trabeculoplasty versus Selective Laser Trabeculoplasty
ARVO 2018
Download Now | | Christine Nguyen: Efficacy and Safety of Micropulse Transscleral Diode Laser Cyclophotocoagulation in the Treatment of Refractory Glaucoma
ASCRS 2018
Download Now | | Cigdem Altan: EARLY CLINICAL OUTCOMES OF MICROPULSED TRANSCLERALCYCLOPHOTOCOAGULATION IN OPEN ANGLE GLAUCOMA
EGS 2018
Download Now | | Dan Nguyen: Micropulse Transscleral Cyclophotocoagulation as a Primary Intervention in Primary Open-Angle Glaucoma Patients
ASCRS 2018
Download Now | | Ihab Ibrahim: No More Blades, Scars or Scares: A One Year Experience of Micropulse Trans-scleral Cyclophotocoagulation from Middle East
WOC 2018
Download Now | | Kareem Moussa: Histologic changes following continuous and micropulse transscleral cyclophotocoagulation: a comparative study
AGS 2018
Download Now | | Karim Ghazal: Early Result of Micro Pulse Cyclophotocoagulation in Glauacoma Cases Resistant to Medication
WOC June 2018
Download Now | | Krishna Patel: Effects of Micropulse Transscleral Cyclodiode Laser on Secondary Open-Angle Glaucoma
ASRCS 2018
Download Now | | Leonard Seibold: Trans-scleral Cyclophotocoagulation: A Tale of Two Probes
ARVO 2018
Download Now | | Marisse Masis: Pupillary mydriasis and recovery after transscleral micropulse cyclophotocoagulation
AGS 2018
Download Now | | Murray Johnstone: Transcleral laser, ciliary muscle shortening & outflow pathway reorganization
ARVO June 2017
Download Now | | Nadiya Kots-Gotlib: Outcomes of Ahmed Valve Implantation Supplemented with Limited Diode Cyclophotocoagulation
AGS 2019
Download Now | | Phornrak Sriphon: EFFICACY OF MICROPULSE TRANSCLERAL CYCLOPHOTOCOAGULATION IN UNCONTROLLED GLAUCOMA AT SRINAGARIND HOSPITAL,THAILAND
WGC 2017
Download Now | | Robert Dionisio: MLT vs SLT in the Hispanic and African American Population for Treatment of Open-Angle Glaucoma
ARVO 2018
Download Now | | Satar Baghrizabehi: MICROPULSE YELLOW LASER TRABECULOPLASTY
WGC 2017
Download Now | | Shotaro Asano: IOP Reduction and Morphological Changes of Ciliary Body by Micropulse Transscleral Cyclophotocoagulation
WOC June 2018
Download Now | | Ted Deng: MLT (Micropulse Laser Trabeculoplasty) or Not?
AGS 2018
Download Now | | Walid Zbiba: MICROPULSED TRANSCLERAL CYCLOPHOTOCOAGULATION IN GLAUCOMAMANAGEMENT: THE TUNISIAN EXPERIENCE
EGS 2018
Download Now |
FREQUENTLY ASKED QUESTIONS
How can I order the MicroPulse P3 Device? The MicroPulse P3 Device comes in a box of six. To place an order, speak with your local sales rep or distributor, or contact customer service at 650.962.8100 or customerservice@iridex.com. What is the CPT code? CPT code for cyclophotocoagulation is 66710 What is the shelf life of MicroPulse P3, G-Probe, and G-Probe Illuminate? 3 years Can the MicroPulse P3 Device be reused? No. The MicroPulse P3 Device is Indicated for single-use What is MicroPulse® Technology? MicroPulse technology is a tissue-sparing solution where a continuous-wave laser beam is chopped into a train of tiny, repetitive, low energy pulses separated by a brief rest period which allows tissue to cool between laser pulses.
RESOURCES
- Instructions for use
- Flyer
- Summary of peer-reviewed studies
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